La Crosse Virus Shows Strain-Specific Differences in Pathogenesis
نویسندگان
چکیده
منابع مشابه
La Crosse Virus in Aedes albopictus
L Crosse virus (LACV) is the most common cause of arthropod-borne, pediatric encephalitis in North America. A member of the California serogroup within the family Bunyaviridae and the genus Orthobunyavirus, LACV is enveloped and contains a negative-sense, tripartite genome with segments designated small (S), medium (M), and large (L). Cases of LACV-associated encephalitis, which can be fatal, o...
متن کاملMonoclonal antibodies against La Crosse virus.
Monoclonal antibodies have been used to show that an epitope is present on the G1 glycoprotein of prototype La Crosse virus that is absent or significantly altered on several isolates of La Crosse virus made in New York State, U.S.A. The portion of the G1 protein where this epitope is located plays a role in both virus neutralization and haemagglutination. Additional experiments revealed that u...
متن کاملLa Crosse virus soluble cell culture antigen.
A virus-free soluble antigen, obtained by ammonium sulfate precipitation of the supernatant fluids of La Crosse virus-infected BHK-21 cell cultures, was more reactive and more specific than infected suckling mouse brain antigen when compared by immunodiffusion and counterelectrophoresis tests. By complement fixation tests, the antigen was cross-reactive with heterologous California group arbovi...
متن کاملComparative Sequence Analyses of La Crosse Virus Strain Isolated from Patient with Fatal Encephalitis, Tennessee, USA
We characterized a La Crosse virus (LACV) isolate from the brain of a child who died of encephalitis-associated complications in eastern Tennessee, USA, during summer 2012. We compared the isolate with LACV sequences from mosquitoes collected near the child's home just after his postmortem diagnosis. In addition, we conducted phylogenetic analyses of these and other sequences derived from LACV ...
متن کاملLa Crosse Virus in Aedes albopictus Mosquitoes, Texas, USA, 2009
We report the arthropod-borne pediatric encephalitic agent La Crosse virus in Aedes albopictus mosquitoes collected in Dallas County, Texas, USA, in August 2009. The presence of this virus in an invasive vector species within a region that lies outside the virus's historically recognized geographic range is of public health concern.
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ژورنال
عنوان ژورنال: Pathogens
سال: 2021
ISSN: 2076-0817
DOI: 10.3390/pathogens10040400